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DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis

✍ Scribed by Lorenz-Depiereux, Bettina; Bastepe, Murat; Benet-Pagès, Anna; Amyere, Mustapha; Wagenstaller, Janine; Müller-Barth, Ursula; Badenhoop, Klaus; Kaiser, Stephanie M; Rittmaster, Roger S; Shlossberg, Alan H

Book ID: 109919422
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 138 KB
Volume: 38
Category: Article
ISSN: 1061-4036
DOI: 10.1038/ng1868

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## Abstract DMP1 is an acidic phosphorylated protein with the spatial and temporal expression that is largely restricted to bone and tooth tissues. The biological function of DMP1 is associated with biomineralization of bone, cartilage and tooth development. To study the cell‐specific expression of