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Dll4-selective Notch signaling induces ephrinB2 gene expression in endothelial cells

✍ Scribed by Tatsuya Iso; Toshitaka Maeno; Yuichi Oike; Miki Yamazaki; Hiroshi Doi; Masashi Arai; Masahiko Kurabayashi


Book ID
116292218
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
450 KB
Volume
341
Category
Article
ISSN
0006-291X

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Endothelin-1 (ET-1) is a potent vasoconstrictor peptide synthesized and secreted by vascular endothelial cells. Regulation of ET-1 production occurs at the level of gene transcription. We previously demonstrated a role for arachidonic acid as an intracellular mediator in the regulation of gene expre