PARP-1 modulates deferoxamine-induced HI
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Rubén Martínez-Romero; Esther Martínez-Lara; Rocío Aguilar-Quesada; Andreína Per
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Article
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2008
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John Wiley and Sons
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English
⚖ 413 KB
## Abstract Poly(ADP‐ribose) polymerase‐1 (PARP‐1) is a nuclear protein that, once activated by genotoxic agents, modulates the activity of several nuclear proteins including itself. Previous studies have established that PARP‐1 inhibition may provide benefit in the treatment of different diseases,