DJ-1 is a Parkinson's disease susceptibility gene in southern Italy
✍ Scribed by EV De Marco; G Annesi; P Tarantino; G Nicoletti; D Civitelli; D Messina; F Annesi; G Arabia; M Salsone; F Condino; F Novellino; G Provenzano; FE Rocca; C Colica; M Morelli; V Scornaienchi; V Greco; L Giofrè; A Quattrone
- Book ID
- 110888924
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 495 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0009-9163
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## Abstract ## __Objective__ The __UCHL‐1__ gene is widely cited as a susceptibility factor for sporadic Parkinson's disease (PD). The strongest evidence comes from a meta‐analysis of small studies that reported the S18Y polymorphism as protective against PD, after pooling studies of white and Asi
## Abstract Recent studies have reported an association between the glucocerebrosidase (__GBA__) gene and Parkinson's disease (PD). To elucidate the role of this gene in our population, we screened 395 PD patients and 483 controls from southern Italy for the N370S and the L444P mutations. We found