Background: A twofold or greater risk of neural tube defect (NTD)-affected pregnancy has been associated with prepregnant obesity, where obesity was defined as body mass index (BMI) of ΟΎ29 kg/m 2 . Risks have been more elevated for spina bifida than for anencephaly. ## Methods: We investigated whe
Dizygotic twinning in mothers of spina bifida
β Scribed by Journel, H. ;Le Marec, B. ;Opitz, John M.
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 85 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0148-7299
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The inheritance of spontaneous dizygotic (DZ) twinning was investigated in 1,422 threegeneration pedigrees ascertained through mothers of spontaneous DZ proband twins. DZ twinning was modelled as a trait expressed only in women. The penetrance was modelled first as a parity independent and secondly
## Abstract Spina bifida myelomeningocele (SBM) is a specific type of neural tube defect whereby the open neural tube at the level of the spinal cord alters brain development during early stages of gestation. Some structural anomalies are virtually unique to individuals with SBM, including a comple