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Dizocilpine prevents the development of tolerance to the sedative effects of diazepam in rats

✍ Scribed by Sandra E. File; Cathy Fernandes

Book ID
113226216
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
369 KB
Volume
47
Category
Article
ISSN
0091-3057

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Acute administration of lorazepam (0.25 and 0.5 mg/kg) and triazolam (0.075-0.25 mg/kg) significantly reduced the locomotor activity of rats placed in a holeboard for 10 min. Acute injections of lorazepam (0.25 and 0.5 mg/kg) and triazolam (0.05-0.25 mg/kg) also significantly reduced exploration, me