𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Divinyl Ketone as Michael Acceptor

✍ Scribed by Dr. Dietrich Spitzner


Book ID
101546746
Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
110 KB
Volume
17
Category
Article
ISSN
0044-8249

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✦ Synopsis


In the course of our investigations on the synthesis of tricyclic sesquiterpenes such as seychellene ( I ) we attempted the preparation of the closely related compound 3,8-dimethyltricyclo[5.3.1.03~8]undecan-2,6-dione (6) in one operation via three consecutive Michael additions.

( I ) , X = CH2


πŸ“œ SIMILAR VOLUMES


Chloroacetylenes as Michael acceptors. I
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The condensation of certain enolates with trichloroethylene to yield a-dichlorovinyl ketones has been shown to proceed by way of dichloroacetylene as an obliqatory intermediate. In a recent communication we described a novel condensation of certain enolates with CI2C= CHCI to yield cl-dichlorovinyl

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Preparation of methylene-gem~fluorocyclopropanes 3 was achieved through the selenoxide elimination reaction derived from gem-difluorocyclopropylmethanols I, while this method can not be applied to non-fluorinated cyclopropylmethanols. The methylene-gem~fluorocyclopropane 3 showed a high reactivity a