𝔖 Bobbio Scriptorium
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Divining the serpin inhibition mechanism: a suicide substrate ‘springe’?

✍ Scribed by Richard A. Engh; Robert Huber; Wolfram Bode; Andreas J. Schulze


Book ID
114152082
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
718 KB
Volume
13
Category
Article
ISSN
0167-7799

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Suicide substrates are widely used in enzymology for studying enzyme mechanisms and designing potential drugs. The presence of a reversible modifier decreases or increases the rate of substrate-induced inactivation, with evident physiological and experimental consequences. To date, only the action o