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Diversity of mutations and distribution of single nucleotide polymorphic alleles in the human α-l-iduronidase (IDUA) gene

✍ Scribed by Li, Peining; Wood, Tim; Thompson, Jerry N


Book ID
123615446
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
711 KB
Volume
4
Category
Article
ISSN
1098-3600

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ot-L-iduronidase (IDUA), which when deficient causes mucopolysaccharidosis type I, is located near the Huntington disease locus (HD) on human Chromosome (Chr) 4p16.3, approximately 10 6 base pairs (bp) from the telomere. As part of our continuing efforts to define a detailed comparative map for this