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Diversity of mechanisms involved in aromatase regulation and estrogen action in the brain

✍ Scribed by Thierry D. Charlier; Charlotte A. Cornil; Gregory F. Ball; Jacques Balthazart


Book ID
116272172
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
802 KB
Volume
1800
Category
Article
ISSN
0304-4165

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Compared with adult mammals, the brain of teleost fish is characterized by an extremely high capacity to aromatize androgens into estrogens, and this metabolic activity results from the expression of a specific brain aromatase (AroB) generated by the cyp19b gene. In this study, we first generated an