Diversity of fatty acid-binding protein structure and function: studies with fluorescent ligands
β Scribed by Judith Storch
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 783 KB
- Volume
- 123
- Category
- Article
- ISSN
- 0300-8177
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π SIMILAR VOLUMES
Binding affinity and binding-pocket polarity is determined for intracellular fatty acid-binding protein (FABP) from aerobic muscle of Chaenocephalus aceratus, the Antarctic icefish, and from rat heart. FABPs bind fatty acids via weak-bond forces (both ionic and hydrophobic), and these bond forces ar
Equilibrium constants for the binding of protoporphyrin to serum albumin and hemopexin and liver cytosolic fatty acid-binding protein of the rat were determined fluorometrically. The experimental equilibrium constant [10(6) M-1 (mean +/- S.D.)] values were 8.4 +/- 1.3, 10.0 +/- 2.4 and 34.0 +/- 3.0