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Diverse Cyclization Catalyzed by In(OTf) 3 for the Convergent Assembly of Substituted Tetrahydrofurans and Tetrahydropyrans

✍ Scribed by Loh, Teck-Peng; Hu, Qi-Ying; Tan, Kui-Thong; Cheng, Hin-Soon


Book ID
120333743
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
54 KB
Volume
3
Category
Article
ISSN
1523-7060

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Diastereoselective construction of cis 2
✍ Teck-Peng Loh; Jian-Ying Yang; Li-Chun Feng; Yan Zhou πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 129 KB

Diastereoselective construction of 2,6-disubstituted tetrahydropyrans with an exocyclic double bond was achieved via the In(OTf) 3 -catalyzed intramolecular 2,5-oxonium-ene cyclization. Its application was further demonstrated by the synthesis of a common intermediate for both zampanolide and dactyl