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Divergent effects of fluoroaluminates on the peptide chain elongation factors EF-Tu and EF-G as members of the GTPase superfamily

โœ Scribed by Jeroen R. Mesters; J.Martien de Graaf; Barend Kraal


Book ID
115927290
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
491 KB
Volume
321
Category
Article
ISSN
0014-5793

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โœ Senyene Eyo Hunter; Linda L Spremulli ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 535 KB

During protein biosynthesis, elongation factor Tu (EF-Tu) delivers aminoacyl-tRNA (aa-tRNA) to the A-site of ribosomes. This factor is highly conserved throughout evolution. However, several key residues differ between bacterial and mammalian mitochondrial EF-Tu (EF-Tu mt ). One such residue is Ser2