Dithionite-mediated perfluoroalkylation of furan derivatives with dimerization

✍ Scribed by Stefan Tews; Martin Hein; Ralf Miethchen

• Publisher: Elsevier Science
• Year: 2002
• Tongue: French
• Weight: 166 KB
• Volume: 43
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)02176-1

✦ Synopsis

2,5-Dimethylfuran (1) and 2-pivaloyloxymethylfuran (4) were alkylated with 1-iodo-perfluorohexane using sodium dithionite as radical initiator. Perfluorohexylation in the 2-position accompanied with dimerization was observed forming the products 2, 3 and 5, respectively.