A series of boron-containing benzoxaborole compounds was designed and synthesized for a structureactivity relationship investigation surrounding 7-(HOOCCH 2 CH 2 )-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (1) with the goal of discovering a new antimalarial treatment. Compound 1 demonstrates the best
Diterpenoid alkaloids as a new class of antiarrhythmic agents. Structure-activity relationship
✍ Scribed by F. N. Dzhakhangirov; M. N. Sultankhodzhaev; B. Tashkhodzhaev; B. T. Salimov
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 821 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0009-3130
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## Abstract Based on a novel lead compound 4‐methylpiperazine‐1‐carbodithioic acid 3‐cyano‐3,3‐diphenylpropyl ester **1**, the systematic structural modification was carried out. All the synthesized compounds were evaluated for their __in‐vitro__ anticancer activities on four to six different cell