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Disulfide Bond As a Switch for Copper-Zinc Superoxide Dismutase Activity in Asthma

✍ Scribed by Ghosh, Sudakshina; Willard, Belinda; Comhair, Suzy A.A.; Dibello, Patricia; Xu, Weiling; Shiva, Sruti; Aulak, Kulwant S.; Kinter, Michael; Erzurum, Serpil C.

Book ID
125503278
Publisher
Mary Ann Liebert
Year
2013
Tongue
English
Weight
556 KB
Volume
18
Category
Article
ISSN
1523-0864

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✍ S.L. Jewett; A.M. Rocklin πŸ“‚ Article πŸ“… 1994 πŸ› Elsevier Science 🌐 English βš– 463 KB

\(N, N^{\prime}\)-Diethyldithiocarbamate reacts with copper in the copper-zinc superoxide dismutase (EC 1.15.1.1) in polyacrylamide gels to form stable yellow-brown bands that are quantifiable at \(448 \mathrm{~nm}\). This method of examining superoxide dismutase has been applied to crude extracts o