Distrubution and metabolism in syrian golden hamsters of 4=(methylnitrosamino)=1=(3=pyridyl)=1= butanone (NNK), a tebacco-specific careinogen
✍ Scribed by Tjälve, Hans; Castonguay, Andre
- Book ID
- 122905437
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 140 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0378-4274
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## Abstract Urinary metabolites of the tobacco‐specific nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK), 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) and its glucuronides, termed total NNAL, have recently been shown to be good predictors of lung cancer risk, years before di
## Abstract ## BACKGROUND In the United States, Blacks who smoke cigarettes have a higher mean blood concentration of the nicotine metabolite cotinine than White smokers. It has not been determined whether there are racial differences in the exposure to the cigarette smoke carcinogen 4‐(methylnitr