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Distribution of β-glucosidase and β-glucuronidase activity and of β-glucuronidase gene gus in human colonic bacteria

✍ Scribed by Marta Dabek; Sheila I. McCrae; Valerie J. Stevens; Sylvia H. Duncan; Petra Louis


Book ID
109303131
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
199 KB
Volume
66
Category
Article
ISSN
0168-6496

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GUSB, the gene for beta-glucuronidase, has been localized to the proximal long arm of chromosome 7 between 7q11.2 and 7q22. Deficiency of beta-glucuronidase results in mucopolysaccharidosis type VII (MPS VII, Sly syndrome). The enzymatic defect has been demonstrated in cultured skin fibroblasts, leu