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Distribution of sphingosine 1-phosphate, a bioactive sphingolipid, in rat tissues

✍ Scribed by Yutaka Yatomi; Robert J. Welch; Yasuyuki Igarashi


Book ID
117107267
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
291 KB
Volume
404
Category
Article
ISSN
0014-5793

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## Abstract Sphingosine‐1‐phosphate (Sph‐1‐P) is an essential bioactive sphingolipid metabolite that has currently become the focus of intense interest. Sph‐1‐P is generated by the enzyme sphingosine kinase (SphK) in response to diverse stimuli, including growth factors, cytokines, and G‐protein‐co