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Distribution of sequence differences in influenza N9 neuraminidase of tern and whale viruses and crystallization of the whale neuraminidase complexed with antibodies

โœ Scribed by Gillian M. Air; R.G. Webster; P.M. Colman; W.G. Laver


Book ID
116075237
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
741 KB
Volume
160
Category
Article
ISSN
0042-6822

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The binding of the Fab fragment of monoclonal antibody NC10 to influenza virus N9 neuraminidase, isolated from tern and whale, was measured using an optical biosensor. Both neuraminidases, homotetramers of 190 kDa, were immobilized to avoid multivalent binding, and the binding of the monovalent NC10