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Distribution of Proteins Implicated in Excitation-Contraction Coupling in Rat Ventricular Myocytes

✍ Scribed by Scriven, David R.L.; Dan, Pauline; Moore, Edwin D.W.

Book ID: 118513686
Publisher: Biophysical Society
Year: 2000
Tongue: English
Weight: 736 KB
Volume: 79
Category: Article
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(00)76506-4

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## Abstract Intracellular Na^+^ concentration ([Na^+^]~i~) is very important in modulating the contractile and electrical activity of the heart. Upon electrical excitation of the myocardium, voltage‐dependent Na^+^ channels open, triggering the upstroke of the action potential (AP). During the AP,