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Distribution of N-type Ca2+ channel binding sites in rabbit brain following central administration of ω-conotoxin GVIA

✍ Scribed by Sarah L. Whorlow; Richard E. Loiacono; James A. Angus; Christine E. Wright

Book ID: 117098768
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 750 KB
Volume: 315
Category: Article
ISSN: 0014-2999
DOI: 10.1016/s0014-2999(96)00592-4

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## Abstract __ω__‐Conotoxin GVIA is a potent, irreversible antagonist of __N__‐type voltage gated Ca^2+^ channels. A radiofluorinated analogue of GVIA could be useful in assessing regional synaptic density of the brain, __in vivo__, using positron emission tomography. __N__‐hydroxy succinimidyl 4‐[