Distribution of hepatitis C virus genotypes in beta-thalassaemic patients from Northern India
โ Scribed by A. Chakravarti; V. Verma
- Book ID
- 110869021
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 104 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0958-7578
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Hepatitis C virus shows substantial nucleotide sequence diversity distributed throughout the viral genome. In the present study genotyping for Hepatitis C virus (HCV) infected patients was based on RFLP analysis of 5 0 UTR and using type specific primers of NS5B regions. It was observed that 60% of
Hepatitis C virus (HCV) shows substantial nucleotide sequence diversity distributed throughout the viral genome, with many variants showing only 68-79% overall sequence homology. This has led to problems in diagnosis of HCV using commercial immunoassays. Based on clustering of homologous sequences,