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Distribution of heat shock proteins in kidneys of rats after immunosuppressive treatment with cyclosporine A

โœ Scribed by Alessandra Stacchiotti; Rita Rezzani; Paola Angoscini; Giovanni Corsetti; Rossella Bianchi

Book ID
117850654
Publisher
Elsevier Science
Year
2001
Tongue
German
Weight
404 KB
Volume
103
Category
Article
ISSN
0065-1281

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Distribution kinetics of FK-506, a novel
Distribution kinetics of FK-506, a novel immunosuppressant, after intravenous administration to rats in comparison with cyclosporin A
โœ Kanji Takada; Hisato Usuda; Mamoru Oh-Hashi ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 588 KB

The distribution kinetics of a novel potent immunosuppressant, FK-506 (FK) has been studied in comparison with cyclosporin A (CyA) both in vivo and in vitro using blood specimens. The infusion studies on FK, 5.0mg kg-1 through the portal and femoral veins showed that the mean hepatic extraction rati