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Distribution of glyoxalase I (GLO) variants in Western Europe and the Indian subcontinent

โœ Scribed by Bhaskara R. Busi; Linda J. Wells; W. S. Volkers; Alida Cornelia Ebeli-Struijk; P. Meera Khan

Publisher
Springer
Year
1979
Tongue
English
Weight
444 KB
Volume
49
Category
Article
ISSN
0340-6717

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โœฆ Synopsis

English, Italian (including Sardinian), and Spanish populations from Europe and Muslim, Hindu, Sikh, Punjabi, and other populations from the Indian subcontinent currently living either in Birmingham or in India were screened for electrophoretically detectable genetic variants of red cell glyoxalase I (GLO), and their frequencies were reported. All the western European populations investigated, including those reported, exhibited an incidence of close to 44% for the GLO1 gene. The frequency distribution of the GLO1 gene in various populations from the Indian subcontinent, in contrast, was found to range between 0.15 and 0.33. These observations suggest that the European populations in general are genetically more homogeneous than are the populations of the Indian subcontinent.

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