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Distribution of conduritol B epoxide in the animal model for Gaucher's disease (Gaucher mouse)

✍ Scribed by Stephens, M.Carla; Bernatsky, Aniko; Singh, Harmeet; Kanfer, Julian N.; Legler, Günter

Book ID
122405842
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
214 KB
Volume
672
Category
Article
ISSN
0304-4165

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## Abstract ## Background Gaucher disease is the most common of the lysosomal storage disorders. The primary manifestation is the accumulation of glucosylceramide (GL‐1) in the macrophages of liver and spleen (Gaucher cells), due to a deficiency in the lysosomal hydrolase glucocerebrosidase (GC).