Distribution of CAG repeats in normal. and Huntington's disease patients in Israel
โ Scribed by E. Gazit; L. Lubomirov; O. Munakov; A. Topper; M. Frydman; K. Fried; Z. Borochovitz; N. Dangoor; A. Bogolubou; HJA Carp
- Book ID
- 110887868
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 152 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0009-9163
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Huntington's disease (HD) is a neurodegenerative and hereditary disease characterized by progressive movement disorders and mental and behavioral abnormalities. The HD gene is an expanding and unstable trinucleotide repeat (CAG repeat sequences). We studied 77 individuals from 38 families with HD in
## Abstract The objective of this study was to further explore the effect of CAG repeat length on the rate of clinical progression in patients with Huntington's disease. The dataset included records for 569 subjects followed prospectively at the Baltimore Huntington's Disease Center. Participants w