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Distribution of breakpoints induced by etoposide and X-rays along the CHO X chromosome

โœ Scribed by Martínez-López, W.; Folle, G.A.; Cassina, G.; Méndez-Acuña, L.; Di-Tomaso, M.V.; Obe, G.; Palitti, F.

Book ID
121253134
Publisher
S. Karger AG
Year
2004
Tongue
French
Weight
125 KB
Volume
104
Category
Article
ISSN
1424-8581

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Down syndrome (DS) individuals are known to be predisposed to develop leukemia and their lymphocytes are highly sensitive to the induction of chromosome aberrations by X-rays. A study was conducted to identify the chromosome breakpoints and to evaluate whether site specificity for chromosome breakag