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Distribution of bile acid transport capacities in the human ileum

✍ Scribed by Matthias Stelzner; Sivagurunathan Somasundaram; David J. Kearney

Book ID
119425507
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
186 KB
Volume
118
Category
Article
ISSN
0016-5085

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Ileal expression of the apical sodium-dependent bile acid transporter (ASBT) in the rat is unaffected by bile salts, yet in the mouse it is under negative-feedback regulation. The bile acid responsiveness of human ASBT is unknown. The human ASBT promoter linked to a luciferase reporter was studied i