Disulfide-linked dimers of human adrenal
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Christine L. Gee; Amanda Nourse; A-Yen Hsin; Qian Wu; Joel D. Tyndall; Gary L. G
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Article
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2005
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Elsevier Science
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English
β 588 KB
The crystal structure of human phenylethanolamine N-methyltransferase (hPNMT) reveals a disulfide-linked dimer, despite the presence of reducing agent in the crystallisation conditions. By removing the reducing agent, hPNMT crystals grow more rapidly and at lower protein concentrations. However, it