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Distribution, biochemistry and function of striatal adenosine A2A receptors

โœ Scribed by Per Svenningsson; Catherine Le Moine; Gilberto Fisone; Bertil B Fredholm


Book ID
117457863
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
596 KB
Volume
59
Category
Article
ISSN
0301-0082

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A 2A adenosine receptors are expressed on immune cells including neutrophils, lymphocytes, eosinophils, monocytes/macrophages, and mast cells. Activation of A 2A receptors on these cells stimulates an increase in [cyclic AMP] i and causes a diminution of inflammatory responses. In mast cells, degran