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Distribution and Retention of Cadmium in Metallothionein I and II Null Mice

โœ Scribed by Jie Liu; Yaping Liu; Anna E. Michalska; K.H.Andy Choo; Curtis D. Klaassen

Book ID
112266024
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
175 KB
Volume
136
Category
Article
ISSN
0041-008X

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Chronic combined exposure to cadmium and
Chronic combined exposure to cadmium and arsenic exacerbates nephrotoxicity, particularly in metallothionein-I/II null mice
โœ Jie Liu; Yaping Liu; Sultan M Habeebu; Michael P Waalkes; Curtis D Klaassen ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 420 KB

Cadmium (Cd) and arsenic (As) are important inorganic toxicants in the environment. Humans certainly have the potential to be exposed to the mixtures of Cd and As, but the toxicological interactions of these inorganic mixtures are poorly defined. Metallothionein (MT) is a cysteine-rich, metal-bindin