Electron microscope immunocytochemistry was used to determine the intracellular localization and distribution among follicular elements of four peptides: calcitonin, somatostatin, calcitonin gene-related peptide (CGRP), and substance P in the thyroid glands of bats captured in the prehibernation pha
Distribution and regulation of substance P-related peptide in the frog visual system
✍ Scribed by Elizabeth A. Debski
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 164 KB
- Volume
- 54
- Category
- Article
- ISSN
- 1059-910X
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✦ Synopsis
Abstract
Modulation of visual signal activity has consequences for both signal processing and for activity‐dependent structuring mechanisms. Among the neuromodulatory agents found in visual areas are substance P (SP)‐related peptides. This article reviews what is known about these substances in the amphibian retina and optic tectum with special emphasis on the leopard frog, Rana pipiens. It is found that the distribution of these SP‐related peptides is remarkably similar to that seen in mammals. This suggests that study of model amphibian systems may significantly enhance our understanding of how neuropeptides contribute to visual system function and organization. Microsc. Res. Tech. 54:220–228, 2001. © 2001 Wiley‐Liss, Inc.
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