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Distorting Malaria Peptide Backbone Structure to Enable Fitting into MHC Class II Molecules Renders Modified Peptides Immunogenic and Protective

✍ Scribed by Cifuentes, Gladys; Patarroyo, Manuel Elkin; Urquiza, Mauricio; Ramirez, Luis E.; Reyes, Claudia; Rodriguez, Raul

Book ID: 126231883
Publisher: American Chemical Society
Year: 2003
Tongue: English
Weight: 318 KB
Volume: 46
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm020440w

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Developing a rational methodology for obtaining vaccines against P. falciparum malaria (the disease's most lethal form, afflicting more than 250 million people around the world per year and killing about 2 million of them) [1] has become one of the main objectives of public health authorities around