Distinguishing adenocarcinoma from mesothelioma in effusions
โ Scribed by Jean H. Triol; Alfred S. Conston; Stephen Van D. Chandler
- Book ID
- 119484590
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 118 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1532-8392
No coin nor oath required. For personal study only.
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## BACKGROUND. Cadherins are a family of cell-cell adhesion proteins. The homotypic binding of cadherins is critical for cell sorting and tissue formation during organogenesis. Different cadherin subtypes show lineage specific tissue expression, which has been exploited to differentiate histologic
## BACKGROUND. The differentiation between malignant mesothelioma and adenocarcinoma based on morphology alone can be a diagnostic challenge. The majority of the available antibodies recognize molecules expressed by adenocarcinoma whereas to the authors' knowledge specific markers for mesothelial