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Distinctive IgVH gene segments usage and mutation status in Chinese patients with chronic lymphocytic leukemia

✍ Scribed by Lijuan Chen; Yaping Zhang; Wenjuan Zheng; Yujie Wu; Chun Qiao; Lei Fan; Wei Xu; Jianyong Li


Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
199 KB
Volume
32
Category
Article
ISSN
0145-2126

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Chronic lymphocytic leukaemia (CLL) with increased prolymphocytes (CLL/PL) has been defined by the World Health Organization (WHO) classification and considered as a progressive and clinically aggressive variant of CLL. To further characterize the biological features of this disease, we performed Ig