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Distinctive DNA methylation patterns of cell-free plasma DNA in women with malignant ovarian tumors

✍ Scribed by Thomas E. Liggett; Anatoliy Melnikov; Qilong Yi; Charles Replogle; Wei Hu; Jacob Rotmensch; Aparna Kamat; Anil K. Sood; Victor Levenson

Book ID
113962636
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
879 KB
Volume
120
Category
Article
ISSN
0090-8258

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## Abstract Abnormal DNA methylation is a feature of most types of cancer, which is reflected in cell‐free circulating DNA in plasma. It is, however, unknown whether surgical removal of the tumor and subsequent therapy induces changes in plasma DNA methylation, which can be used to monitor treatmen