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Distinction of carcinogens from mutagens by induction of liver cell foci in a model for detection of initiation activity

✍ Scribed by Hiroki Sakai; Tetsuya Tsukamoto; Masami Yamamoto; Kiyoshi Kobayashi; Hirofumi Yuasa; Toshio Imai; Tokuma Yanai; Toshiaki Masegi; Masae Tatematsu


Book ID
117467278
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
100 KB
Volume
188
Category
Article
ISSN
0304-3835

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Intraperitoneal injection of d-galactosa
✍ Yoshiji Asaoka; Hiroki Sakai; Naofumi Takahashi; Akihiro Hirata; Tetsuya Tsukamo πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 419 KB πŸ‘ 1 views

In an in vivo 5-week initiation assay model, chemical hepatectomy by hepatotoxicant administration was utilized as a cell proliferation stimulus as an alternative to the two-thirds partial hepatectomy. The study investigated the effect of an intraperitoneal (i.p.) injection of D-galactosamine (D-gal