Distinction of acute lymphoblastic leukemia from acute myeloid leukemia through microarray-based DNA methylation analysis

Genome-wide analysis of acute myeloid le

Genome-wide analysis of acute myeloid leukemia with normal karyotype reveals a unique pattern of homeobox gene expression distinct from those with translocation-mediated fusion events

✍ Silvana Debernardi; Debra M. Lillington; Tracy Chaplin; Simon Tomlinson; John Am 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 626 KB

## Abstract Gene expression profiles were determined from presentation peripheral blood and bone marrow samples of 28 patients with acute myeloid leukemia (AML). Hierarchical clustering sorted the profiles into separate groups, each representing one of the major cytogenetic classes in AML [i.e., t(