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Distinction between Human Cytochrome P450 (CYP) Isoforms and Identification of New Phosphorylation Sites by Mass Spectrometry

โœ Scribed by Redlich, Gorden; Zanger, Ulrich M.; Riedmaier, Stephan; Bache, Nicolai; Giessing, Anders B. M.; Eisenacher, Martin; Stephan, Christian; Meyer, Helmut E.; Jensen, Ole N.; Marcus, Katrin


Book ID
126094939
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
992 KB
Volume
7
Category
Article
ISSN
1535-3893

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Cytochrome P450 (CYP) proteins are involved in the biological oxidation and reduction of xenobiotics, affecting the pharmacological efficiency of drugs. This study aimed to establish a method to simultaneously quantify 11 CYP isoforms by multiplexed-multiple reaction monitoring analysis with liquid