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Distinction at the leading edge of the cell

✍ Scribed by Paul Timpson; Roger J. Daly

Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 182 KB
Volume: 27
Category: Article
ISSN: 0265-9247
DOI: 10.1002/bies.20213

No coin nor oath required. For personal study only.

✦ Synopsis

Cell locomotion is governed by spatially and temporally co-ordinated changes in the organization of the actin cytoskeleton. In the highlighted manuscript, (1) the authors focus on actin remodelling at the front of moving cells to reveal the existence of two distinct yet spatially overlapping actin networks that play largely independent yet fundamental roles in cell migration. The first is defined

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