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Distinct temporospatial expression patterns of glycolysis-related proteins in human hepatocellular carcinoma

✍ Scribed by Katjana Daskalow; David Pfander; Wilko Weichert; Nadine Rohwer; Armin Thelen; Peter Neuhaus; Sven Jonas; Bertram Wiedenmann; Christoph Benckert; Thorsten Cramer


Publisher
Springer
Year
2009
Tongue
English
Weight
837 KB
Volume
132
Category
Article
ISSN
1432-119X

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Treatment of hepatocellular carcinoma (HCC) by chemotherapy is often impeded by the intrinsic multidrug resistance (MDR) of this frequent primary cancer of the liver. The MDR phenotype can be caused by ATP-dependent export of chemotherapeutic drugs across the plasma membrane being mediated by transp