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Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations

✍ Scribed by Sergei Roumiantsev; Daniela S Krause; Carola A Neumann; Christopher A Dimitri; Frances Asiedu; Nicholas C.P Cross; Richard A Van Etten

Book ID
114413410
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
916 KB
Volume
5
Category
Article
ISSN
1535-6108

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## Abstract 8p11 myeloproliferative syndrome (EMS) is a clinical‐pathologic entity characterized by rearrangements involving the __FGFR1__ gene, which encodes a receptor tyrosine kinase. These rearrangements invariably lead to aberrant fusion proteins in which the kinase activity is constitutively