We have previously described the expression of a functional full-length trkC transcript for neurotrophin-3 (NT-3) receptor in oligodendroglia (OL) cells (Kumar and de Vellis, 1996). To date, the role of NT-3 and its signal transduction cascade in OL remains poorly defined. We report that the NT-3 re
โฆ LIBER โฆ
Distinct roles for PI3K in proliferation and survival of oligodendrocyte progenitor cells
โ Scribed by Sylvie Ebner; Maryse Dunbar; Randall D. McKinnon
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 148 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0360-4012
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GATA-3 is a zinc-finger transcription factor that is essential for both early T cell development and Th2 cell differentiation. To quantify GATA-3 expression during T cell development in vivo in the mouse, the GATA-3 gene was targeted by insertion of a lacZ reporter by homologous recombination in emb