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Distinct resident and recirculating memory T cell subsets in non-lymphoid tissues

✍ Scribed by Carbone, Francis R; Mackay, Laura K; Heath, William R; Gebhardt, Thomas


Book ID
120980767
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
366 KB
Volume
25
Category
Article
ISSN
0952-7915

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Memory T cells are heterogeneous in expression of lymph node homing receptors, delineating "central-memory" (T CM , CD62L hi /CCR7 + ) and "effector-memory" (T EM , CD62L lo /CCR7 -) subsets that migrate to lymphoid and non-lymphoid tissues, respectively. It is not known how these subsets arise or h