HIV-1 Tat mutants in the cysteine-rich r
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Giovanna Tosi; Andrea De Lerma Barbaro; Antonella D'Agostino; Maria Teresa Valle
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Article
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2000
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John Wiley and Sons
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English
β 178 KB
Human macrophage and T cell lines were stably transfected with HIV-1 wild-type Tat or Tat mutants in the cysteine-rich region displaying trans-dominant negative effects on HIV-1 life cycle. The expression of HLA class I and class II molecules was not affected by wild-type Tat. Tat mutants, instead,