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Distinct regulation of CD40-mediated interleukin-6 and interleukin-12 productions via mitogen-activated protein kinase and nuclear factor κB-inducing kinase in mature dendritic cells

✍ Scribed by Yoshiki Yanagawa; Kazunori Onoé


Book ID
108781840
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
271 KB
Volume
117
Category
Article
ISSN
0019-2805

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## Abstract Blood vessel injury results in limited oxygen tension and diffusion leading to hypoxia, increased anaerobic metabolism, and elevated production of acidic metabolites that cannot be easily removed due to the reduced blood flow. Therefore, an acidic extracellular pH occurs in the local mi