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Distinct mechanisms of action of tumor necrosis factor antagonists: What are the clinical implications?

✍ Scribed by William F.C. Rigby


Book ID
113899674
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
51 KB
Volume
34
Category
Article
ISSN
0049-0172

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The potential mechanisms of interferon (1FN)-gamma and tumor necrosis factor (TNF)-alpha action on tumor cells have been investigated in a model of mouse fibroblasts transformed by distinct retroviral vectors carrying the v-mos, c-myc, and v-Ha-ras oncogene, respectively. Treatment with both cytokin