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Distinct FAK-Src activation events promote α5β1 and α4β1 integrin-stimulated neuroblastoma cell motility

✍ Scribed by Wu, L; Bernard-Trifilo, J A; Lim, Y; Lim, S-T; Mitra, S K; Uryu, S; Chen, M; Pallen, C J; Cheung, N-Kv; Mikolon, D

Book ID: 110072758
Publisher: Nature Publishing Group
Year: 2007
Tongue: English
Weight: 676 KB
Volume: 27
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1210770

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## Abstract α4β1 integrin is highly expressed in lymphocytes and is essential in hematopoiesis, extravasation, and the inflammatory response. α4β1 can be activated by intracellular signals elicited upon T‐cell activation by phorbol esters, CD3 crosslinking, or certain chemokine/receptor interaction