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Distinct ErbB receptor binding and signaling of neuregulin-1 splicing isoforms

✍ Scribed by Ran Wang; Yuriko Iwakura; Nobuyuki Takei; Yuta Ishizuka; Yingjun Zheng; Taisuke Kato; Shigeki Higashiyama; Hiroyuki Nawa

Book ID
116777637
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
69 KB
Volume
68
Category
Article
ISSN
0168-0102

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## Abstract Neuregulin‐1 (NRG‐1) proteins promote Schwann cell survival, differentiation and proliferation during development. High levels of an NRG‐like activity are also present in some human peripheral nerve sheath tumors, suggesting that NRG‐1 isoforms may be involved in the development of thes